top of page
0B9A0960.jpg

Host
Defence

0B9A1115 klein.jpg

Host - Bacteria interactions

Mycobacterium tuberculosis

In collaboration with the group of Prof. Tom Ottenhoff, dr. Simone Joosten and Amy de Waal (Dept. of Infectious Diseases, LUMC), we study M. tuberculosis infection of bronchial and alveolar epithelial cells.

IMG_6702_edited.jpg
wit.jpg
wit.jpg
wit.jpg
0B9A1115 klein.jpg

Host - Bacteria interactions

Microbiota

In collaboration with TNO we aim to develop a long-term microbial co-culture on primary nasal epithelial cultures.

0B9A1428_edited.jpg
wit.jpg
wit.jpg
wit.jpg
0B9A0960.jpg

Host - Virus interactions

Rhinovirus

We study host-virus infections with focus on Rhinovirus as an important contributor to COPD and asthma exacerbations. We study anti-viral immunity in patient-derived materials and for example in connection to whole cigarette smoke exposure.

IMG-20210520-WA0005_edited.jpg
0B9A1451_edited.jpg
wit.jpg
wit.jpg
ALI day 14 BR541 20x C.jpg

Host - Virus interactions

Farm Dust

Together with the department of Parasitology (dr. Hermelijn Smits) we investigate protective effects of farm dust exposure of the airway epithelium in the context of asthma.

IMG-20210520-WA0005_edited.jpg
wit.jpg
wit.jpg
wit.jpg
wit.jpg
cilia%20tw_edited.jpg

Antimicrobial Peptides

Host Defense Peptides

In collaboration with the group of dr. Mark de Boer (Dept. of Infectious Diseases, LUMC) we study the role of host defense peptides in antibiotic-resistant infections.

0B9A1428_edited.jpg
wit.jpg
wit.jpg
wit.jpg
wit.jpg
bottom of page