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Host
Defence

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Host - Bacteria interactions

Mycobacterium tuberculosis

In collaboration with the group of Prof. Tom Ottenhoff, dr. Simone Joosten and Amy de Waal (Dept. of Infectious Diseases, LUMC), we study M. tuberculosis infection of bronchial and alveolar epithelial cells.

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Host - Virus interactions

SARS-CoV-2

Together with the departments of Medical Microbiology and CCB, we study SARS-CoV-2 biology in different regions of the lung and in comparison to other coronaviruses.

Annemarie
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Host - Virus interactions

Rhinovirus

We study host-virus infections with focus on Rhinovirus as an important contributor to COPD and asthma exacerbations. We study anti-viral immunity in patient-derived materials and for example in connection to whole cigarette smoke exposure.

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Host - Virus interactions

Farm Dust

Together with the department of Parasitology (dr. Hermelijn Smits) we investigate protective effects of farm dust exposure of the airway epithelium in the context of asthma.

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Antimicrobial Peptides

Host Defense Peptides

In collaboration with the group of dr. Peter Nibbering (Dept. of Infectious Diseases, LUMC) we study the role of host defense peptides in antibiotic-resistant respiratory infections.

Patrick Lennart
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