PulmoScience Lab
Epithelial
(dys)function
Tissue damage
Epithelial Remodeling
We use primary epithelial cell cultures for studies on airway epithelial remodeling in COPD, ILD and lung cancer.
Tissue damage
Pulmonary fibrosis
We use Organoid and Transwell cultures to investigate the biology of radiation-induced lung fibrosis.
Tissue damage
COVID-19 lung damage
We use primary alveolar cell cultures and organoid technology in combination with the Lung-Chip to develop a human cell culture model of COVID-19-related lung damage.
Tissue damage
AATD Biomarkers
We assess biomarkers to study effects of AAT therapy in patients with Alpha-1 Antitrypsin-related emphysema.
Regeneration
MSC therapy
Using a variety of technologies, we study emphysematous lung tissue obtained before and after mesenchymal stem cell (MSC) therapy to identify markers of repair and/or altered immune responses.
Lung cancer
Tumor Recurrence
Using Organoid and Lung-Chip technology, we study NSCLC tumor characteristics to identify patients at risk for recurrence.