We use primary epithelial cell cultures for studies on airway epithelial remodeling in COPD, ILD and lung cancer.
We use Organoid and Transwell cultures to investigate the biology of radiation-induced lung fibrosis.
COVID-19 lung damage
We use primary alveolar cell cultures and organoid technology in combination with the Lung-Chip to develop a human cell culture model of COVID-19-related lung damage.
We assess biomarkers to study effects of AAT therapy in patients with Alpha-1 Antitrypsin-related emphysema.
Using a variety of technologies, we study emphysematous lung tissue obtained before and after mesenchymal stem cell (MSC) therapy to identify markers of repair and/or altered immune responses.
Using Organoid and Lung-Chip technology, we study NSCLC tumor characteristics to identify patients at risk for recurrence.